Literature Detail
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
这篇文献会作为平台方法、软件或流程的证据来源，用于帮助理解方法背景和应用边界。
Authors
作者信息
用于判断研究团队、方法出处和后续引用线索。
Stephen G. Landt, Georgi K. Marinov, Anshul Kundaje, Pouya Kheradpour, Florencia Pauli, Serafim Batzoglou, Bradley E. Bernstein, Peter Bickel, James B. Brown, Philip Cayting, Yiwen Chen, Gilberto DeSalvo, Charles Epstein, Katherine I. Fisher-Aylor, Ghia Euskirchen, Mark Gerstein, Jason Gertz, Alexander J. Hartemink, Michael M. Hoffman, Vishwanath R. Iyer
Abstract
摘要
先读摘要确认研究问题、方法贡献和适用数据类型，再进入关联流程复现。
This comprehensive paper provides guidelines and best practices for ChIP-seq experiments as developed by the ENCODE and modENCODE consortia. It addresses antibody validation, library complexity, sequencing depth, replication, and data analysis standards that have become foundational references for the chromatin biology community.